#4
Disease Areas
- Solid tumors (with focus in Lung and GI cancers)
- Hematologic malignancies (with focus in AML)
Topics of Interest (Research associated with the above disease areas will be prioritized)
- Data-driven novel target identification through cutting-edge platforms utilizing human cells or patient-derived samples (e.g., single-cell/spatial omics, CRISPR screen, and data integration via AI/ML pipeline)
- Novel therapeutic approaches to modulate tumor microenvironment via targeting tumor-intrinsic pathways, stromal cells, adaptive/innate immune cells, etc.
- Enabling technologies for innate immune cell therapies and cell engagers
- Drug delivery systems for selective tumor or immune/stromal cell targeting (preferably addressing challenges associated with selectivity/safety/immunogenicity)
- Clinically translatable animal models or human in vitro/ex-vivo assay systems that reflect tumor microenvironment of patients (e.g., humanized models, organoids)